| When the Smoke Clears: Sixty 6, Sixty 1 | Album | June 13, 2000 | — |
| The Real Slim Shady | Single | June 12, 2000 | — |
| Daiquiri Factory: Cocaine Raps, Volume 2 | Album | June 6, 2000 | — |
| The Summer | Single | June 5, 2000 | — |
| Comme un aimant | Album | May 25, 2000 | Soundtrack |
| The Marshall Mathers LP | Album | May 22, 2000 | — |
| Balance & Options | Album | May 16, 2000 | — |
| Incognegro | Album | May 16, 2000 | — |
| Simply the Best | Album | May 15, 2000 | Compilation |
| Fettes Brot für die Welt | Album | May 12, 2000 | Compilation |
| Verbal Kenkuzhionz | Album | May 9, 2000 | — |
| Hybrid Theory | Album | May 7, 2000 | — |
| Da draußen | Single | April 25, 2000 | — |
| Vivrant Thing | Single | April 24, 2000 | — |
| What Am I? | EP | April 18, 2000 | — |
| Yeeeah Baby | Album | April 4, 2000 | — |
| The Worst | Album | March 28, 2000 | — |
| Year 2000 | Single | March 28, 2000 | — |
| The Greatest Hits | Album | March 27, 2000 | Compilation |
| Touche d’espoir | Album | March 27, 2000 | — |
| Chapter One: Testing the Waters | EP | March 14, 2000 | — |
| Before the Willennium | Album | March 7, 2000 | Compilation |
| BTNHResurrection | Album | February 29, 2000 | — |
| Memphis Under World | Album | February 22, 2000 | Compilation |
| Try Again | Single | February 22, 2000 | Soundtrack |
| Get Up | Single | February 18, 2000 | — |
| Speak of Da Devil | Album | February 15, 2000 | — |
| Secret Songs: The Unreleased Album | Album | February 14, 2000 | Compilation |
| Tabula Rasa, Part II | Single | February 4, 2000 | — |
| Snoop Dogg presents Tha Eastsidaz | Album | February 1, 2000 | — |
| Youngest of Da Camp | Album | January 27, 2000 | — |
| Supreme Clientele | Album | January 25, 2000 | — |
| Feelin’ So Good | Single | January 24, 2000 | — |
| Diagnol Ryme Garganchula | EP | January 17, 2000 | — |
| Be All You Can Be | EP | January 1, 2000 | — |
| Madlib Remixes | EP | January 1, 2000 | Compilation, Remix |
| Tragic Epilogue | Album | January 1, 2000 | — |
| $$$ | Single | 2000 | — |
| 2002 | Album | 2000 | Compilation |
| 24 Hrs. w/a G | Single | 2000 | — |
| 3-6 Feet Underground (The Unreleased Demon) | Album | 2000 | — |
| 5th Power Presents: Talib Kweli featuring Million | EP | 2000 | — |
| ?! | Album | 2000 | — |
| After da Kappa 2000 | Album | 2000 | DJ-mix, Mixtape/Street |
| American Men, Volume 1 | Album | 2000 | — |
| Back in Dissniss | Album | 2000 | — |
| Back on da Block | Single | 2000 | — |
| Back On Da Block (DJ Krush Rmx) | Single | 2000 | Remix |
| Back On Up | Single | 2000 | — |
| Balance & Options (Sampler) | EP | 2000 | — |
| Between Me and You | Single | 2000 | — |
| Beyond the Spiral: B-Sides and Rarities | Album | 2000 | Compilation |
| Bitch Betta Have My Money 2001 | Album | 2000 | — |
| Bitch Please II | Single | 2000 | — |
| Bootleg: From the Lost Vault, Volume 1 | Album | 2000 | Compilation |
| Bounce with Me | Single | 2000 | — |
| Bow Wow (That’s My Name) | Single | 2000 | — |
| Boyz ’n The Hood: Going Back To My Roots | Album | 2000 | Compilation |
| Brooklyn Blocks BW Last Bref | Single | 2000 | — |
| Cakes | Single | 2000 | — |
| Can U C the Pride in the Panther | Single | 2000 | — |
| Can’t Give It Up | Single | 2000 | — |
| Center of Attention | Album | 2000 | — |
| Change the World | Single | 2000 | — |
| Childs Play | Album | 2000 | — |
| Choppin' Em Up 4 | Album | 2000 | — |
| Choppin' Em Up Part 3 | Album | 2000 | — |
| Chronik | Single | 2000 | — |
| Classik | Single | 2000 | — |
| Come Back In One Piece | Single | 2000 | Soundtrack |
| Coming Soon | Album | 2000 | Mixtape/Street |
| Conflict / The Booth | Single | 2000 | — |
| Confused? You Should Be | Album | 2000 | Compilation |
| Diagnol Ryme Garganchula 2.0 | EP | 2000 | — |
| Esclave 2000 | Single | 2000 | — |
| F**K Action 21 | Album | 2000 | — |
| Fa Shiesty Cats | Single | 2000 | — |
| Fatta förstå | Single | 2000 | — |
| Fehdehandschuh | Single | 2000 | — |
| Fire | Single | 2000 | — |
| Focus | Single | 2000 | — |
| Forever Gold | Album | 2000 | Compilation |
| Gandalf's Beat Machine | Album | 2000 | — |
| Gangster Theme Music | Album | 2000 | Compilation |
| Ghostface Meets MF: Operation Ironman | Album | 2000 | — |
| Gold 2000 | Album | 2000 | Compilation |
| Golden Collection 2000 | Album | 2000 | Compilation |
| Gravel Pit | Single | 2000 | — |
| Greatest Hits | Album | 2000 | Compilation |
| Hello | Single | 2000 | — |
| Hidden Chambers, Volume 1 | Album | 2000 | Compilation |
| Husslin' | EP | 2000 | — |
| Hypnotize Camp Posse | Album | 2000 | — |
| I Don't Wanna / Come Back In One Piece | Single | 2000 | Soundtrack |
| I Like Dem Girlz / Just a Bitch | Single | 2000 | — |
| I Speak The Truth | Single | 2000 | — |
| If You Must | Single | 2000 | — |
| It’s So Hard | Single | 2000 | — |
| Killer 2000 | Single | 2000 | — |
| King of Rap | Single | 2000 | — |