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- Chuck DCity: Long IslandStarted in: 1980s
- Chucky ThompsonCity: Washington, D.C.Started in: 1990s
- ChuuweeStarted in: 1990sCountry: United States
- Cities AvivStarted in: 1980sCountry: United States
- CJCity: New York CityStarted in: 2010s
- CL SmoothCity: New RochelleStarted in: 1980s
- Clams CasinoStarted in: 1980sCountry: United States
- Clark KentStarted in: 1980sCountry: United States
- Coi LerayCity: BostonStarted in: 2010s
- Coke La RockStarted in: 1970sCountry: United States
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- Colt FordStarted in: 1970sCountry: United States
- CommonCity: ChicagoStarted in: 1990s
- ConsequenceCity: QueensStarted in: 1990s
- CoolioStarted in: 1960sCountry: United States
- CordaeCity: RaleighStarted in: 2010s
- Corey JacksonCity: JacksonStarted in: 2010s
- Count Bass DStarted in: 1970sCountry: United States
- Cowboy TroyStarted in: 1970sCountry: United States
- CozzCity: Los AngelesStarted in: 2010s
- Craig BrockmanCity: Los AngelesStarted in: 1990s
- Craig GCity: QueensStarted in: 1980s
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- Cris Molo AkapoStarted in: 2010sCountry: United States
- Crooked ICity: Long BeachStarted in: 1990s
- CupcakKeCity: ChicagoStarted in: 2010s
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- Cut ChemistCity: New YorkStarted in: 1990s
- Cyhi the PrynceCity: Stone MountainStarted in: 2000s
- Cymphonique MillerCity: Los AngelesStarted in: 2000s
- C‐BoStarted in: 1970sCountry: United States
- D SmokeCity: InglewoodStarted in: 2000s
- D The BusinessStarted in: 2000sCountry: United States
- D-DotCity: BrooklynStarted in: 1990s
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- Da BratCity: ChicagoStarted in: 1990s
- DaBabyCity: ClevelandStarted in: 2010s
- Daddy XStarted in: 1980sCountry: United States
- DaedelusCity: Santa MonicaStarted in: 2000s
- Dame GreaseCity: HarlemStarted in: 1990s
- Damian MartinezCity: LaredoStarted in: 2010s
- Damu the FudgemunkStarted in: 1980sCountry: United States
- Damu the FudgemunkCity: Washington, D.C.Started in: 2000s
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- Danny BrownStarted in: 1980sCountry: United States
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- Danny!City: KilleenStarted in: 2000s
- Dante SantiagoCity: Los AngelesStarted in: 1980s
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- Dave EastStarted in: 1980sCountry: United States
- David BannerStarted in: 1970sCountry: United States
- David Jude JolicoeurCity: BrooklynStarted in: 1980s
- David RushCity: Highland ParkStarted in: 2000s
- David StonesCity: BrooklynStarted in: 2000s
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- DawinCity: BrooklynStarted in: 2010s
- Dawn RobinsonCity: New LondonStarted in: 1980s
- DaxStarted in: 1990sCountry: United States
- Daz DillingerStarted in: 1970sCountry: United States
- Da’ T.R.U.T.H.Started in: 1970sCountry: United States
- DC GlennCity: ChicagoCountry: United States
- DD OsamaCity: HarlemStarted in: 2010s
- DeadleeCity: Los AngelesStarted in: 2000s
- Dee BarnesStarted in: 1980sCountry: United States
- Dee Dee RamoneCity: Fort LeeStarted in: 1960s
- Dee WatkinsCity: JacksonvilleCountry: United States
- DeeBabyCity: HoustonCountry: United States
- Dee‐1Started in: 1980sCountry: United States
- Def JefCity: HarlemStarted in: 1980s
- DefariCity: Los AngelesCountry: United States
- Dej LoafCity: DetroitStarted in: 2010s
- Del the Funky HomosapienStarted in: 1970sCountry: United States
- Del the Funky HomosapienCity: OaklandStarted in: 1980s
- DemrickStarted in: 1980sCountry: United States
- Dennis FerrerStarted in: 1970sCountry: United States
- Denzel CurryCity: Carol CityStarted in: 2010s
- Derek MinorStarted in: 1980sCountry: United States
- DesiignerCity: BrooklynStarted in: 2010s
- DeStorm PowerCity: Arlington CountyStarted in: 2000s
- Destroy LonelyCity: AtlantaStarted in: 2010s
- DetailCity: DetroitStarted in: 2000s
- DeuceCity: Los AngelesStarted in: 2000s
- Deuce MayneCity: JacksonCountry: United States
- DevCity: TracyStarted in: 2000s
- DeVante SwingCity: HamptonStarted in: 1980s
- Devin the DudeCity: St. PetersburgStarted in: 1990s
- Devon HendryxStarted in: 1980sCountry: United States
- DeyonCountry: United StatesGenres: hip-hop
- DiamondCity: AtlantaStarted in: 2000s
- Diamond pistolsStarted in: 2010sCountry: United States